Mouse Anti-Chicken CD8a-UNLB MBS673960 from MyBioSource.com

Product Specs
ItemMouse Anti-Chicken CD8a-UNLB
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS673960
ReactivityChicken (Ck)
ClonalityMonoclonal
NCBI Gene Aliaseszgc:136643
NCBI Full Gene NameCD8a molecule
ApplicationsFCM, IHC-fr, IHC-p, IP
Immunogenalpha chain of chicken CD8 (Mr 34 kDa)
In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1,2 Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.3 MAb EP72 recognizes the CD8 alpha chain
Antibody TypeSecondary
HostMouse
CloneEP72
Molecular Weight24,017 Da
IsotypeIgG2b kappa
TargetCD8 alpha
FormatPurified (UNLB) Antibody
Conjugate/TagUnconjugated
Quantity0.5 mg